Tuesday, August 24, 2010
ketamine effective at relieving depression??
The traditional form of" ketamine, even though effective at relieving depression", when taken by itself, it can lead to short-term psychotic symptoms. Ketamine can cause side effects, including blurred vision, confusion, drowsiness, increased or decrease blood pressure or heart beat, metal or mood changes, nausea, vomiting and nightmares.
Stewart R. and Hirani V from King's College London and University College London Medical School in the United Kingdom published in the July 1, 2010 issue of Psychosomatic Medicine saying depressive symptoms in older people were linked with clinical vitamin D deficiency defined as having 25(OH)D levels lower than 10 ng/mL.
Another study led by May H.T. and colleagues from Intermountain Medical Center in Murray, UT and published in the June 2010 issue of American Heart Journal indicates that vitamin D levels are associated with incident depression among people aged 50 or older who had cardiovascular disease, but no prior history of depression.
Depression affects an estimated 17.5 million men and women in the United States, 9.2 million of whom have major or clinical depression.
It was seen that patients who were not affected by other anti-depressants responded to the drug.
The drug, "ketamine" was even able to reinstate synaptic connections between nerve cells in the brain. Dr. Ronald Duman, Professor of psychiatry and pharmacology at Yale University, who fronted the study, said, "It's like a magic drug — one dose can work rapidly and last for seven to 10 days".
However, George Aghajanian, professor of pharmacology at Yale University and co-researcher on this study said that before ketamine is prescribed to patients for use, further exploration is needed.
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